Date Thesis Awarded

2013

Document Type

Honors Thesis

Degree Name

Bachelors of Science (BS)

Department

Chemistry

Advisor

Jonathan Scheerer

Committee Member

Robert J. Hinkle

Committee Member

Kurt E. Williamson

Abstract

Outlined in this paper is a series of work done towards the construction of bicyclo[2.2.2]diazaoctane structures found in a several natural products. Detailed work is shown for a general method of creating these cores by a domino sequence to rapidly generate these cores with enantio- and diastereoselectivity. A similar sequence this outlined and displayed in the formal synthesis of brevianamide B. This synthesis makes use of a similar domino sequence, but a new source of facial selectivity is used.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Comments

Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.

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