Date Thesis Awarded

5-2010

Document Type

Honors Thesis

Degree Name

Bachelors of Science (BS)

Department

Chemistry

Advisor

John C. Poutsma

Committee Member

Lisa M. Landino

Committee Member

Gary Rice

Committee Member

Jianjun Paul Tian

Abstract

The goal of this experiment was to determine if trends exist in the fragmentation pat- terns of heptapeptides containing lysine and its non-protein amino acid analogs (or- nithine, daba, dapa). Previous research in the laboratory of Dr. J. C. Poutsma on pentapeptides suggested that the length of the side chain on the lysine analog played a role in peptide fragmentation pathways. This study, however, found no such connection between length of side chain and fragmentation patterns suggesting that as a peptide lengthens the flexibility of the peptide bonds outweigh the side chain length factor in determining fragmentation patterns.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Comments

Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.

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