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Honors Theses from 2017

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Electrocatalytic Hydrogen Generation by Cobalt Complexes, Jessica E. Armstrong

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Photocontrol of pH via Doped Conjugated Polymer Nanoparticles, Aaron I. Bayles

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Investigating Biological Properties Utilizing Synthetic Methods, Lindsay E. Chatkewitz

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Advancements in the Photocatalysis of Iron Complexes and the Electrocatalysis of Cobalt Complexes for Hydrogen Generation, Ryan J. DiRisio

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Structural Comparison of Copper(II) Thiocyanate Pyridine Complexes, Joseph V. Handy

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Utilization of Unnatural Amino Acids in Novel Bioconjugates and Probing Applications, Christina A. Howard

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Total synthesis of barettin: Model study of specialized aldol condensation to directly access diketopiperazine targets, Elizabeth W. Kelley

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Improving Water Barrier Properties of Epoxy Coatings with Addition of Graphene Oxide, Sang H. Kim

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Fluorescently-Labeled Glutathiones to Quantify Cysteine Reactivity, Saloni H. Patolia

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Optogenetic Investigations of the PreBötzinger Complex: Support for the Dbx1 Core Hypothesis, Francis D. Pham

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Characterization of Mixed N,S Donor Ligand and Group 12 Metal Complexes with X-Ray Crystallography, ESI-MS, and NMR, Mikhaila D. Ritz

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Tuning the pKa of Fluorescent Rhodamine pH Probes via Substituent Effects, Sarah G. Stratton

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Development of Novel Chemical Strategies to Modulate Biological Function, Diya M. Uthappa

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Visible Light Fluorescence Switching in Dye-Doped Conjugated Polymer Nanoparticles, Xinzi Zhang

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Connecting Energy Metabolism and Neurodegeneration: Pyruvate Kinase and Oxidative Stress, Julia P. Zuercher

Honors Theses from 2016

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Hydrogen-Bonding Control of Solvatochromism and Non-Radiative Decay in the Fluorescence of 3-Aminofluoren-9-one Derivatives, Isaac Gregory Alty

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Synthesis and Characterization of Interpenetrating Polymer Networks for Applications in Extraterrestrial Radiation Shielding, Josiah Arevalo Hammack

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Iron Complexes for Photocatalytic Hydrogen Generation, Carolyn L. Hartley

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Fragmentation Studies of Lysine and Lysine Analog Containing Tetrapeptides, Zachariah Imran Hasan

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Investigation of Unnatural Amino Acids as a Means to Modulate Protein Function, Taylor Harrison Jacobs

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An Experimental and Theoretical Study of Proton Affinity in Proline-Containing Dipeptides: Exploring the “Proline Effect”, Anton Luke Lachowicz

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Studies of the development of intermolecular networks during the curing of coatings using single-sided nuclear magnetic resonance, Frances Jude Morin

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Total Synthesis of Peramine, a Defensive Alkaloid Produced by Endophytic Fungi of Cool Season Grasses Possessing Anti-Insect Properties, Matthew Rolfe Nelli

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Utilizing Synthetic Tools to Address Biological Issues, Marshall Scott Padilla

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Construction of Bicyclo[2.2.2]diazaoctane Alkaloids via Intermolecular [4+2] Cycloadditions, Jacob Gabriel Robins

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Peptide Fragmentation Studies on Doubly Charged Proline and Pipecolic Acid Containing Pentapeptides and Methods Development for an HPLC/MS Instrument for Proteomics Experiments, Hannah Emily Smith

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The Effect of Ethanol, Methanol, and Water on the Hydrolytic Degradation of Polyamide-11, Patrick Smith

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Creating a Computational Model of Prion Disease in the Human Neocortex, Christina Alexandra Stephens

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Probing Single-Molecule Photophysics of Rhodamines on TiO2, Jenna Adrienne Uy Tan

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Domino Reactions Involving Merged Cycloaddition and Cycloreversion Processes Affording Pyridine Products, Jill Williamson

Honors Theses from 2015

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Initiation of Photochemical Reactions via FRET from Fluorescent Conjugated Polymer Nanoparticles, Christian Chamberlayne

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First-­‐Row Transition Metal Coordination Compounds for the Electrocatalytic Generation of Hydrogen from Organic and Aqueous Solutions, Patrick M. Crossland

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Novel methodologies to study protein S-glutathiolation using fluorescence spectroscopy, Jacob Daniels

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Diffusion-Based Biomolecular Sensing Using Low-Field NMR, John S. Gray

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The Effect of Functionalized versus Unmodified Graphene Oxide on Polyimide Nanocomposite Properties, Natalie V. Hudson-Smith

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Thiols in Glycolysis: Effects of Cysteine Modification on Pyruvate Kinase Activity, Taylor K. Lain

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Studies Directed Toward the Synthesis of Aristopyridinone A, Maren K. Leibowitz

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Electro- and Photocatalytic Generation of Hydrogen by Iron Polypyridyl Complexes, Kathryn J. Mayer

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Development of Novel Chemical Techniques to Address Biological Questions, Johnathan C. Maza

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Investigation of the interaction between graphene oxide and a biopolymer surface, Pei Pang

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Development of a Site-Selective Protein Immobilization Methodology Utilizing Unnatural Amino Acids, Benjamin K. Raliski

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High Performance Co-Polyimide Synthesis for Cosmic Radiation Shielding, Jarrell H. Raper

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Synthesis and Characterization of pH-Sensitive Rhodamine 6G Spirolactam Structures, Grace H. Taumoefolau

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Unnatural Amino Acids in Proteins for Development of Novel Biochemical Tools, Jordan Villa

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The Electro- and Photocatalytic Activity of a Ni-NNSS Schiff-Base Complex for Hydrogen Generation, Catherine F. Wise

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Cu(I) Networks With Polycyanoaromatic Ligands, Congqi Yang

Honors Theses from 2014

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An Iron Polypyridyl Electrocatalyst for Hydrogen Generation in Aqueous Solutions, Gannon P. Connor

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Synthesis of a Novel Unnatural Amino Acid for Protein Incorporation and Click Mediated Conjugation, Christopher A. Farley

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Increasing the Hydrogen Content of Aromatic Polyimides for Radiation Shielding, Geoffrey T. Geberth

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Evaluation of the Tensile, Water Diffusion, and Water Hydrolysis Properties of Graphene Oxide/Polyamide-11 Composites and Their Synthesis, Christopher Houston Komatsu

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Studies Directed toward the Synthesis of Asymmetric Loline Alkaloids, Kelsey E. Miller

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Modeling Dispersive Electron-Transfer Dynamics in Single Dye Molecules on TiO2, Alana Ogata

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Synthesis and Characterization of Cadmium(II) Complexes with Biologically Inspired Multidentate Ligands, Carolina Rojas Ramirez

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Cobalt Salen Complexes for Catalytic Hydrogen Production, Matthew J. Van Dongen

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Photophysics of Single Rhodamine Dye Molecules on TiO2 Substrates, Natalie Wong

Honors Theses from 2013

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Synthesis and Characterization of Silica-Coated Nanoparticles for Dye-Sensitized Solar Cells, Jacquelyn Blake-Hedges

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Characterization of Polyamide-12; Hydrolysis Kinetics Comparison, and the Study of Crude-oil Pipeline Applications, Charles J. Blevins

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A Mathematical Model of Renal Cell Carcinoma, Taylor M. Broome

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Methodology towards the Construction of Bicyclo[2.2.2]diazaoctane Cores and its Application Towards the Synthesis of Brevianamide B, Alex Chinn

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Design and Synthesis of Novel Hydrogen-Rich Polyimides for Radiation Shielding, David J. Hill

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Effects of coal transportation on heavy metal contamination in wetland environments along the Virginia Peninsula, John Lovette

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Copper(I) Bromide and Copper(I) Iodide Complexes of Aliphatic Diamine and Tetramine Ligands, Shannon M. McCullough

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Mass Spectrometry-based Proteomics Experiments and Peptide Fragmentation Studies of Lysine and its Homologues, Charlotte B. Platner

Honors Theses from 2012

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Fabrication and Evaluation of Copper(I) Iodide Sensor Substrates, Lars Erik Dunaway

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Synthesis of 1-(6-(dimethylamino)naphthalen-2-yl)-2,2-dimethylpropan-1-one as a Fluorescent Probe of Solvent Acidity in HSA, Amy Michele Green

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Preparation of Spirooxazine-Functionalized Conjugated Polymer Nanoparticles by Click Chemistry, Elena A. Lepekhina

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Potential of PRODAN derivatives as chemosensors of the microacidity of cyclodextrin host-guest complexes, Hannah R. Naughton

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Are Twisted Derivatives of PRODAN More Effective than Planar Derivatives as Detectors of Solvent Acidity in Micellar Solutions?, Zachariah Bach Nealy

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Hydrogen Deuterium Exchange of Lysine Homologs and Construction of a Nanospray Ionization Source, Rita N. Straus

Honors Theses from 2011

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Bismuth Reagents in Organic Chemistry: Structural and Mechanistic Studies, Stephen Ammann

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Mechanical Properties of Solvent Cast Graphene-Polymer Nanocomposites, Joseph Christesen

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Hypothiocyanous Acid Oxidation of Tubulin Cysteines Inhibits Microtubule Polymerization, Hillary Meghan Clark

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Investigation of Copper(I) Cyanide for Use as a Luminescent Sensor Device, Matthew Dembo

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Evaluation of Micro-Preconcentrators and Solid Phase Microextraction Fibers for MEMS-based Gas Chromatography Systems, Ashley Marie Hoover

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Convenient, Bismuth Mediated, One-pot, Two Component Synthesis of 2,6-Disubstituted-3,4-Dihydropyrans, Robert Frederick Lambert

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Synthesis of 1-(5-methylhexyl)-2,3,8,9-tetrahydro-1H-naphtho[2,1-e]indol-6(7H)-one, Nicholas Lopez

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Absorption of Various Small Organic Acid-water and Alcohol-water Solutions into Polyamide-11, Kyle Overdeep

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The Production of Novel Poly(arylene ethers) for Use as Radiation Shielding in Outer Space, Ellen Hutchins Speers

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Characterization of Novel d10 Metal Ion Complexes of Multidentate Ligands by X-ray Crystallography and 1H NMR Spectroscopy, Pei Wang

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Gas-Phase Thermochemistry of Non-Protein Amino Acids by the Extended Kinetic Method, Vincent James Yannello

Honors Theses from 2010

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Investigations of the Fragmentation Spectra of Heptapeptides Containing Lysine and its Non-Protein Amino Acid Homologs, Douglas William Challener

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Photomodulation of Conjugated Polymer Nanoparticles via Photochromic Dye Doping, Christina Marie Davis

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The Detection of Methionine Sulfoxide in Tubulin and Glyceraldehyde 3-Phosphate Dehydrogenase, Tara D. Hagedorn

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The Synthesis and Subsequent Fluorescence Studies of Spirooxazine-Functionalized Poly(phenylene vinylene) Using the Gilch Polymerization Technique, Kathryn Anne Peth

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Formation of Highly Electrically Conductive Surface-Silvered Polyimide Films Under Exceptionally Mild Conditions, Tyler Stukenbroeker

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Preparation and Study of a Rare Ternary Insulating Magnet, Thomas J. Wallin

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Methods to Study Tubulin S-glutathionylation, Anna Jean Wirth

Honors Theses from 2009

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Monomer and Polyimide Production for Radiation Shielding Purposes in Manned Space Exploration, Norah Bate

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Investigations of the Fragmentation Spectra of Peptides Containing Lysine and its Non-Protein Amino Acid Homologs, Matthew Cooke Bernier

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A Computational Investigation of FTY720P-Mediated Neuroprotection in Multiple Sclerosis, Hannah C. Cohen

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Synthesis and Luminescent Behavior of Piperazinium Chlorocuprates(I) and Copper(I) Iodide and Bromide Complexes of Aliphatic Diamine Ligands, Jacob Edwin Kuperstock

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Structure and Luminescence of Copper(I) Cyanide Networks Incorporating Monoamine, Diamine, and Monoimine Ligands, Amanda Noelle Ley

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Spontaneous Amide Bond Formation of Amino Acids in Aqueous Solution, Sarah Joan Milam

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Bismuth(III) Catalyzed Cyclic Ether Syntheses, Lee Colyer Speight

Honors Theses from 2008

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Molecular Hydrogen: A theoretical investigation into the one electron densities of the first three 1Σ+g states, Jefferson Bates

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Effect of Interstitial Impurities on the Residual Resistivity of Niobium Thin Films, Justin Connell

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Toward Biologically Active 2,6-Disubstituted Dihydropyran Ring Systems Using an Environmentally Benign Bismuth Catalyst and Mukaiyama Aldol Reaction, Lauren Katkish

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Synthesis and Characterization of Copper(I) Halide and Nitrate Complexes of Heterocyclic Thioureas, Aakarsh Saxena

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Gas-Phase Acidities and Proton Affinities of Amino Acid Analogs from the Extended Kinetic Method, Ian Webb